SCHEMBL11755322

SCHEMBL11755322

O=C1N(c2cc(Cl)cc(Cl)c2)C(=O)C12CC2

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
ELANE P08246 2/20 0.39
BCL2A1 Q16548 1/20 0.38
PGR P06401 2/20 0.37
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
ADRB1 P08588 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
ALDH1A1 P00352 2/20 0.36
USP2 O75604 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ITGAL P20701 3/20 0.36
ITGB2 P05107 2/20 0.36
ICAM1 P05362 2/20 0.36
ITGA4 P13612 1/20 0.35
ITGB7 P26010 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Procymidone SCHEMBL23093 0.75 TSHR (1.00) TSHRELANEBCL2A1ALDH1A1USP2
Procymidone SCHEMBL9806377 0.74 TSHR (0.96) TSHRELANEBCL2A1ALDH1A1USP2
SCHEMBL13879569 0.71 POLB (0.54) TSHRITGAL
Dimethachlon SCHEMBL410360 0.70 TSHR (0.50) TSHRBCL2A1CHRM2CHRM4ADRB1
SCHEMBL10268369 0.70 ALDH1A1 (0.50) TSHRBCL2A1CHRM2CHRM4ADRB1
SCHEMBL10170730 0.68 TSHR (0.58) TSHRELANEBCL2A1ALDH1A1USP2
SCHEMBL3171879 0.67 MGLL (0.62) TSHRALDH1A1
SCHEMBL11754451 0.67 ALDH1A1 (0.55) TSHRBCL2A1CHRM2CHRM4ADRB1
SCHEMBL158206 0.65 AR (0.55) TSHRELANEBCL2A1ALDH1A1ITGAL
SCHEMBL11170138 0.65 AR (0.56) TSHRPGRITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4009278-A Antimicrobial composition and method containing N-(3,5-dihalophenyl)-imide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-02-22 US disclosed