Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CEL | P19835 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837337 | 0.75 | ALDH1A1 (0.45) | DAOALDH1A1MAPTHTTCA2 | |
| SCHEMBL11603069 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL11759784 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL7537433 | 0.68 | DRD4 (0.49) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL6965403 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRSMN1; SMN2GAA | |
| SCHEMBL274753 | 0.66 | ALDH1A1 (0.72) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL11834986 | 0.66 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL11736214 | 0.66 | ALDH1A1 (0.44) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 | |
| SCHEMBL14472613 | 0.65 | ALDH1A1 (0.46) | ALDH1A1MAPTTSHRSMN1; SMN2GAA | |
| SCHEMBL11762213 | 0.64 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007207-A | HYPOTENSIVE, ANTIDEPRESSANT, ANALGESIC, ANTICONVULSANT, SEDATIVE, TRANQUILIZER | SHARPS ASSOCIATES (US) | 1977-02-08 | — | — | US | disclosed |