SCHEMBL11837337

SCHEMBL11837337

CCCC1Cc2c(c(=O)oc3cc(CCCC4CCCCC4)cc(O)c23)S1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAPT P10636 1/20 0.45
HTT P42858 2/20 0.39
GAA P10253 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CEL P19835 2/20 0.34
DAO P14920 1/20 0.34
CNR1 P21554 7/20 0.33
CNR2 P34972 7/20 0.33
GPR55 Q9Y2T6 1/20 0.32
DRD4 P21917 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
CA2 P00918 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11834986 0.76 ALDH1A1 (0.56) ALDH1A1MAPTHTTGAATP53
SCHEMBL11756678 0.75 DAO (0.44) ALDH1A1MAPTHTTGAATP53
SCHEMBL11736214 0.74 ALDH1A1 (0.44) ALDH1A1MAPTHTTGAATP53
SCHEMBL11760641 0.69 ALDH1A1 (0.63) ALDH1A1MAPTHTTGAATP53
SCHEMBL274753 0.69 ALDH1A1 (0.72) ALDH1A1MAPTHTTGAATP53
SCHEMBL11603069 0.68 ALDH1A1 (0.61) ALDH1A1MAPTHTTGAATP53
SCHEMBL11738042 0.68 ALDH1A1 (0.61) ALDH1A1MAPTHTTGAATP53
SCHEMBL11738683 0.67 ALDH1A1 (0.60) ALDH1A1MAPTHTTGAATP53
SCHEMBL11739818 0.67 ALDH1A1 (0.60) ALDH1A1MAPTHTTGAATP53
SCHEMBL11834833 0.66 ALDH1A1 (0.56) ALDH1A1MAPTHTTGAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3946111-A ANALYGESICS SHARPS ASSOCIATES (US) 1976-03-23 US disclosed