Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17769822 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TDP1HTTSMN1; SMN2TP53 | |
| SCHEMBL31321473 | 0.81 | AKR1B1 (0.54) | AKR1B1ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL28721173 | 0.81 | AKR1B1 (0.54) | AKR1B1ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL30853117 | 0.80 | GPR35 (0.54) | ALDH1A1TDP1HTTSMN1; SMN2TP53 | |
| SCHEMBL5141227 | 0.80 | GPR35 (0.54) | ALDH1A1TDP1HTTSMN1; SMN2TP53 | |
| SCHEMBL8178061 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TDP1HTTSMN1; SMN2MAPT | |
| SCHEMBL1978371 | 0.79 | MEN1 (0.41) | ALDH1A1TDP1HTTSMN1; SMN2MAPT | |
| SCHEMBL16711728 | 0.79 | GPR35 (0.54) | ALDH1A1TDP1HTTSMN1; SMN2MAPT | |
| SCHEMBL5971372 | 0.79 | AKR1B1 (0.52) | AKR1B1ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL4074396 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1HTTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4036951-A | SUNSCREEN AGENTS | SYNERGISTICS, INC. (US) | 1977-07-19 | — | — | US | disclosed |