Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30853117 | 0.83 | GPR35 (0.54) | MEN1KMT2AGPR35ALDH1A1MAPT | |
| SCHEMBL5141227 | 0.83 | GPR35 (0.54) | MEN1KMT2AGPR35ALDH1A1MAPT | |
| SCHEMBL16711728 | 0.81 | GPR35 (0.54) | MEN1KMT2AGPR35ALDH1A1MAPT | |
| SCHEMBL8178061 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AGPR35ALDH1A1MAPT | |
| SCHEMBL11757407 | 0.79 | AKR1B1 (0.44) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL1977473 | 0.78 | GPR35 (0.43) | MEN1KMT2AGPR35ALDH1A1MAPT | |
| SCHEMBL17182634 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL3549785 | 0.77 | KDM4E (0.39) | MEN1KMT2AALDH1A1MAPTRECQL | |
| SCHEMBL1137222 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AGPR35ALDH1A1MAPT | |
| SCHEMBL11442960 | 0.76 | POLB (0.44) | MEN1KMT2AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326916-A | Combined preparation and application of 2-fluoro-4-allyl-6-nitrophenol and 2-fluoro-4-nitro-6-allyl phenol | UNIV QINGDAO AGRICULTURAL | 2015-02-04 | — | — | CN | disclosed |
| CN-104326916-A | Combined preparation and application of 2-fluoro-4-allyl-6-nitrophenol and 2-fluoro-4-nitro-6-allyl phenol | UNIV QINGDAO AGRICULTURAL | 2015-02-04 | — | — | CN | disclosed |
| US-8227501-B2 | 1,6-dihydro-2H-3-oxa-6-aza-as-indacene compounds | FERRER INTERNACIONAL, S.A. (ES) | 2012-07-24 | — | — | US | disclosed |
| US-8227501-B2 | 1,6-dihydro-2H-3-oxa-6-aza-as-indacene compounds | FERRER INTERNACIONAL, S.A. (ES) | 2012-07-24 | — | — | US | disclosed |
| US-8227501-B2 | 1,6-dihydro-2H-3-oxa-6-aza-as-indacene compounds | FERRER INTERNACIONAL, S.A. (ES) | 2012-07-24 | — | — | US | disclosed |
| EP-2350088-A1 | 1,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | Ferrer Internacional, S.A. (ES) | 2011-08-03 | — | — | EP | disclosed |
| US-20110144178-A1 | 1 ,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-16 | — | — | US | disclosed |
| US-20110144178-A1 | 1 ,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-16 | — | — | US | disclosed |
| US-20110144178-A1 | 1 ,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | FERRER INTERNACIONAL, S.A. (ES) | 2011-06-16 | — | — | US | disclosed |
| WO-2010012789-A1 | 1,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | FERRER INTERNACIONAL S. A. (ES) | 2010-02-04 | — | — | WO | disclosed |
| WO-2010012789-A1 | 1,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | FERRER INTERNACIONAL S. A. (ES) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144178-A1 | 1 ,6-DIHYDRO-2H-3-OXA-6-AZA-AS-INDACENE COMPOUNDS | MTNR1A, MTNR1B, ADORA2A | MEN1 1086/4885KMT2A 895/4885GPR35 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.