Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031257 | 0.85 | ALDH1A1 (0.71) | POLBHSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL27647761 | 0.85 | KMT2A (0.60) | POLBMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL11754904 | 0.83 | ALDH1A1 (0.72) | POLBAKR1C3HSD17B10CDC25ACDC25B | |
| SCHEMBL31022695 | 0.82 | MEN1 (0.62) | AKR1C3HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL758991 | 0.82 | MEN1 (0.62) | AKR1C3HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL7778741 | 0.80 | MEN1 (0.60) | AKR1C3HSD17B10MEN1KMT2ARAB9A | |
| Acetic Acid SCHEMBL6444184 | 0.80 | MEN1 (0.60) | AKR1C3HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL12700378 | 0.80 | ALDH1A1 (0.70) | POLBAKR1C3MEN1KMT2ARAB9A | |
| SCHEMBL27339882 | 0.80 | AKR1C3 (0.79) | POLBAKR1C3HSD17B10CDC25ACDC25B | |
| SCHEMBL13852923 | 0.79 | ALDH1A1 (0.66) | POLBMEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058529-A | Polycyclic amino derivatives of pyrrolidone and piperidone | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |