Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757609 | 0.85 | POLB (0.60) | KMT2AALDH1A1POLBRAB9AMEN1 | |
| SCHEMBL11031257 | 0.82 | ALDH1A1 (0.71) | KMT2AALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL3444657 | 0.82 | KMT2A (0.56) | KMT2AALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL882791 | 0.81 | KCNK3 (0.75) | KMT2AALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL474709 | 0.78 | KMT2A (0.70) | KMT2AALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL10925115 | 0.78 | RECQL (0.63) | ALDH1A1HPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2328579 | 0.77 | ALDH1A1 (0.59) | KMT2AALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL3179857 | 0.77 | RECQL (0.57) | KMT2AALDH1A1POLBRAB9ANPC1 | |
| SCHEMBL2005896 | 0.76 | KCNK3 (0.76) | KMT2AALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL1811041 | 0.76 | KCNK3 (0.81) | KMT2AALDH1A1HPGDKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100562511-C | 2-aryl-acetic acids, their derivative and contain their pharmaceutical composition | DOMPE SPA (IT) | 2009-11-25 | — | — | CN | disclosed |
| CN-1768026-A | 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them | DOMPE SPA (IT) | 2006-05-03 | — | — | CN | disclosed |