Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PPP5C | P53041 | 1/20 | 0.30 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595124 | 0.81 | HSD11B1 (0.30) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL14424191 | 0.76 | KDM4E (0.39) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL16360071 | 0.76 | KDM4E (0.39) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL4359852 | 0.76 | — | — | |
| SCHEMBL15498544 | 0.76 | KDM4E (0.39) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL24843176 | 0.76 | KDM4E (0.39) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL14669163 | 0.76 | — | — | |
| SCHEMBL13444708 | 0.76 | KDM4E (0.39) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL615001 | 0.76 | KDM4E (0.39) | CYP2D6KDM4EGMNNPPM1BLMNA | |
| SCHEMBL2495557 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010289-A | METHOD OF MANUFACTURING SYNTHETIC RESIN FILM HAVING HIGH WRITABILITY AND PRINTABILITY | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-03-01 | — | — | US | disclosed |