Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283118 | 0.82 | MAPT (0.60) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL6541728 | 0.77 | SMN1; SMN2 (0.72) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL7245174 | 0.77 | NPC1 (0.76) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL6707064 | 0.75 | MAPT (0.77) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL1108994 | 0.75 | MMP1 (0.70) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL11701856 | 0.74 | MAPT (0.47) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10575752 | 0.74 | MAPT (0.59) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL10575746 | 0.74 | MAPT (0.58) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL7245504 | 0.73 | MAPT (0.69) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL3103720 | 0.73 | MAPT (0.58) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026891-A | HYPOTENSIVE AGENTS, ANTITHROMBOTICS, AND CARDIOTONICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-31 | — | — | US | disclosed |