Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575746 | 0.84 | MAPT (0.58) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL10576783 | 0.81 | MAPT (0.60) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL7245174 | 0.80 | NPC1 (0.76) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL11758254 | 0.74 | MAPT (0.63) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL10577145 | 0.74 | ADRB2 (0.48) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6541728 | 0.74 | SMN1; SMN2 (0.72) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL15156377 | 0.73 | KMT2A (0.56) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL3103720 | 0.72 | MAPT (0.58) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6707064 | 0.72 | MAPT (0.77) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL11283118 | 0.72 | MAPT (0.60) | MAPTNPC1MAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |