Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | PHGDH | O43175 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758088 | 1.00 | KMT2A (0.58) | KMT2AMEN1PHGDHRAB9AGAA | |
| SCHEMBL1509271 | 1.00 | KMT2A (0.58) | KMT2AMEN1PHGDHRAB9AGAA | |
| Quinoline SCHEMBL11096417 | 0.86 | NPC1 (0.51) | KMT2AMEN1PHGDHRAB9AGAA | |
| Isoquinoline SCHEMBL10997368 | 0.86 | NPC1 (0.46) | KMT2AMEN1PHGDHRAB9AGAA | |
| Cadaverine Tartrate SCHEMBL28015425 | 0.82 | CYP1A2 (0.56) | KMT2AMEN1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11332310 | 0.80 | KMT2A (0.73) | KMT2AMEN1PHGDHRAB9AGAA | |
| SCHEMBL4729142 | 0.80 | KMT2A (0.63) | KMT2AMEN1PHGDHRAB9AGAA | |
| SCHEMBL13390947 | 0.80 | KMT2A (0.63) | KMT2AMEN1PHGDHRAB9AGAA | |
| SCHEMBL175272 | 0.79 | MEN1 (0.71) | KMT2AMEN1PHGDHRAB9AGAA | |
| SCHEMBL113558 | 0.79 | MEN1 (0.71) | KMT2AMEN1PHGDHRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024082-A | DL-N-CYCLOPROPYLMETHYL-3-HYDROXY-9-AZAMORPHINAN | BRISTOL-MYERS COMPANY (US) | 1977-05-17 | — | — | US | claimed |
| US-4024082-A | DL-N-CYCLOPROPYLMETHYL-3-HYDROXY-9-AZAMORPHINAN | BRISTOL-MYERS COMPANY (US) | 1977-05-17 | — | — | US | disclosed |