Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL28789392 | 0.84 | GPR35 (0.64) | CYP1A2TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL8909509 | 0.83 | CYP1A2 (0.61) | CYP1A2TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL8909499 | 0.83 | CYP1A2 (0.61) | CYP1A2TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL1509271 | 0.82 | KMT2A (0.58) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11758703 | 0.82 | KMT2A (0.58) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11758088 | 0.82 | KMT2A (0.58) | MAPTALDH1A1TDP1MEN1KMT2A | |
| Benzene SCHEMBL27733069 | 0.82 | ALDH1A1 (0.65) | TSHRMAPTALDH1A1TDP1GPR35 | |
| Acetic Acid SCHEMBL27721273 | 0.80 | HSD17B10 (0.58) | CYP1A2TSHRMAPTALDH1A1TDP1 | |
| Benzene SCHEMBL27968727 | 0.79 | ALDH1A1 (0.62) | CYP1A2TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL16355165 | 0.79 | HSD17B10 (0.67) | TSHRALDH1A1TDP1GPR35HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529902-A | Method for preparing imidazole through coiled tubing gas phase catalytic reaction | JIANGSU YANJIANG CHEMICAL RESOURCE DEV RES INST CO LTD | 2015-04-22 | — | — | CN | disclosed |