Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759170 | 1.00 | NOS3 (0.46) | NOS3NOS1NOS2KDM4CSLC7A5 | |
| SCHEMBL28575379 | 0.88 | KDM4C (0.42) | KDM4CFAAHKDM4ELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11755571 | 0.85 | KDM4C (0.41) | KDM4CFAAHKDM4ELMNAALDH1A1 | |
| SCHEMBL11754720 | 0.85 | KDM4C (0.46) | KDM4CPKMKIF11FAAHKDM4E | |
| Hydrochloric Acid SCHEMBL11755566 | 0.85 | KDM4C (0.41) | KDM4CFAAHKDM4ELMNAALDH1A1 | |
| SCHEMBL7377233 | 0.84 | KDM4C (0.47) | KDM4CFAAHKDM4ELMNAALDH1A1 | |
| SCHEMBL16815231 | 0.83 | KDM4C (0.46) | KDM4CFAAHKDM4ELMNAALDH1A1 | |
| SCHEMBL16815337 | 0.83 | KDM4C (0.46) | KDM4CFAAHKDM4ELMNAALDH1A1 | |
| SCHEMBL8319482 | 0.79 | KDM4C (0.43) | KDM4CPKMFAAHMEN1LMNA | |
| SCHEMBL15151083 | 0.79 | NOS3 (0.49) | NOS3NOS1NOS2SLC7A5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033956-A | 7[α-Amino-ω-(2,3-methylenedioxy-phenyl)acylamido]cephalosporanic acid derivatives | RICHARDSON-MERRELL INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-3994876-A | 6-[α-AMINO-ω-(2,3-METHYLENEDIOXYPHENYL)ACYLAMIDO]PENICILLANIC ACID DERIVATIVES | RICHARDSON-MERRELL INC. (US) | 1976-11-30 | — | — | US | disclosed |