Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319482 | 0.94 | KDM4C (0.43) | KDM4CFAAHMTNR1ALMNAMT-CO2 | |
| SCHEMBL16815337 | 0.86 | KDM4C (0.46) | KDM4CFAAHMTNR1ALMNAALKBH1 | |
| SCHEMBL16815231 | 0.86 | KDM4C (0.46) | KDM4CFAAHMTNR1ALMNAALKBH1 | |
| SCHEMBL7444911 | 0.85 | HRH4 (0.44) | KDM4CFAAHMTNR1ALMNAMT-CO2 | |
| SCHEMBL11759170 | 0.84 | NOS3 (0.46) | KDM4CFAAHMTNR1ALMNAPOLB | |
| SCHEMBL11759166 | 0.84 | NOS3 (0.46) | KDM4CFAAHMTNR1ALMNAPOLB | |
| SCHEMBL9471736 | 0.81 | KDM4C (0.43) | KDM4CFAAHMTNR1ALMNAALKBH1 | |
| SCHEMBL28575379 | 0.78 | KDM4C (0.42) | KDM4CFAAHMTNR1ALMNAEED | |
| SCHEMBL3402977 | 0.78 | KDM4C (0.50) | KDM4CFAAHMTNR1ALMNAALKBH1 | |
| SCHEMBL23792241 | 0.78 | MGAM (0.42) | KDM4CFAAHMTNR1ALMNAMT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870183-A | RENIN INHIBITORS, HYPOTENSIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0252727-A1 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1988-01-13 | — | — | EP | disclosed |