Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377233 | 0.94 | KDM4C (0.47) | KDM4CFAAHMTNR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18241014 | 0.84 | PPARG (0.43) | PPARGNR4A2 | |
| SCHEMBL7444911 | 0.83 | HRH4 (0.44) | KDM4CFAAHMTNR1ASMN1; SMN2MEN1 | |
| SCHEMBL16815231 | 0.81 | KDM4C (0.46) | KDM4CFAAHMTNR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16815337 | 0.81 | KDM4C (0.46) | KDM4CFAAHMTNR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11759166 | 0.79 | NOS3 (0.46) | KDM4CFAAHMTNR1AMEN1ALDH1A1 | |
| SCHEMBL11759170 | 0.79 | NOS3 (0.46) | KDM4CFAAHMTNR1AMEN1ALDH1A1 | |
| SCHEMBL9471736 | 0.76 | KDM4C (0.43) | KDM4CFAAHMTNR1ASMN1; SMN2MEN1 | |
| SCHEMBL2602430 | 0.76 | EED (0.46) | KDM4CFAAHMTNR1ASMN1; SMN2MGAM | |
| SCHEMBL19502669 | 0.76 | CYP1A2 (0.57) | MEN1KMT2APPARGNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0950054-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012181-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-03-26 | — | — | WO | disclosed |