Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757774 | 0.73 | CA12 (0.49) | ATMALDH1A1LMNATSHRMEN1 | |
| SCHEMBL13544676 | 0.72 | GSTO1 (0.47) | ATMMAPTALDH1A1LMNATSHR | |
| SCHEMBL27000244 | 0.72 | CA12 (0.61) | MAPTALDH1A1LMNAHTTTSHR | |
| SCHEMBL11759264 | 0.72 | CA12 (0.71) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11761968 | 0.71 | LMNA (0.59) | ATMALDH1A1LMNATSHRCA12 | |
| SCHEMBL11415003 | 0.71 | KDM4E (0.56) | ALDH1A1HTTKMT2ACA1CA2 | |
| SCHEMBL10989857 | 0.70 | LMNA (0.57) | ATMMAPTALDH1A1LMNAHTT | |
| SCHEMBL6550026 | 0.70 | ATM (1.00) | ATMALDH1A1LMNATSHRMEN1 | |
| SCHEMBL17465709 | 0.69 | KMT2A (0.62) | MAPTALDH1A1LMNAHTTTSHR | |
| SCHEMBL11762590 | 0.69 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061647-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |