Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | FDPS | P14324 | 9/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764166 | 0.94 | GGPS1 (0.47) | PTPN1FDPSCETPGGPS1 | |
| SCHEMBL11760531 | 0.90 | PTPN1 (0.49) | PTPN1FDPSESR1ESR2 | |
| SCHEMBL11757262 | 0.83 | PTPN1 (0.42) | PTPN1FDPSESR1ESR2 | |
| SCHEMBL11762641 | 0.82 | PTPN1 (0.52) | PTPN1ESR1ESR2 | |
| SCHEMBL5441305 | 0.81 | HDAC1 (0.46) | FDPSESR1ESR2GGPS1 | |
| SCHEMBL11760251 | 0.81 | LMNA (0.38) | PTPN1ESR1ESR2 | |
| SCHEMBL2032074 | 0.80 | FDPS (0.46) | FDPSESR1ESR2GGPS1 | |
| SCHEMBL11406548 | 0.79 | PTPN1 (0.46) | PTPN1FDPSCETPGGPS1 | |
| SCHEMBL11763191 | 0.77 | FDPS (0.48) | FDPSESR1ESR2GGPS1 | |
| SCHEMBL6769521 | 0.77 | FDPS (0.42) | FDPSESR1ESR2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061681-A | Method for the preparation of mono- or poly [dialkyl or dicycloalkylphosphonylmethyl] aromatic carbocyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |