Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.49 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.34 |
| ▸ | EPM2A | O95278 | 1/20 | 0.34 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757262 | 0.92 | PTPN1 (0.42) | PTPN1FDPSESR1ESR2AR | |
| SCHEMBL11759783 | 0.90 | PTPN1 (0.46) | PTPN1FDPSESR1ESR2 | |
| SCHEMBL11764166 | 0.87 | GGPS1 (0.47) | PTPN1FDPS | |
| SCHEMBL11762641 | 0.85 | PTPN1 (0.52) | PTPN1ESR1ESR2ARPGK1 | |
| SCHEMBL11762482 | 0.80 | LMNA (0.36) | PTPN1 | |
| SCHEMBL11761689 | 0.79 | PTPN1 (0.60) | PTPN1PTPRC | |
| SCHEMBL11759232 | 0.78 | PTPN1 (0.45) | PTPN1PGK1PGK2PTPRCPTPN6 | |
| SCHEMBL11764065 | 0.75 | FDPS (0.46) | FDPSPGK1PGK2 | |
| SCHEMBL11760251 | 0.72 | LMNA (0.38) | PTPN1ESR1ESR2 | |
| SCHEMBL11761399 | 0.72 | FDPS (0.52) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061681-A | Method for the preparation of mono- or poly [dialkyl or dicycloalkylphosphonylmethyl] aromatic carbocyclic compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |