Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11756674 | 0.87 | ALDH1A1 (0.59) | AKR1C3AKR1C2ALDH1A1MAPK1TDP1 | |
| SCHEMBL453183 | 0.85 | AKR1C3 (0.68) | AKR1C3AKR1C2ALDH1A1MAPK1TDP1 | |
| SCHEMBL11787404 | 0.84 | MEN1 (0.57) | AKR1C3AKR1C2ALDH1A1MAPK1TDP1 | |
| SCHEMBL397773 | 0.82 | MAPK1 (0.77) | AKR1C3AKR1C2ALDH1A1MAPK1TDP1 | |
| SCHEMBL20587939 | 0.82 | FABP4 (0.53) | AKR1C3AKR1C2ALDH1A1TDP1MEN1 | |
| SCHEMBL2312520 | 0.81 | ALDH1A1 (0.60) | AKR1C3AKR1C2ALDH1A1MAPK1TDP1 | |
| SCHEMBL27527050 | 0.81 | AKR1C3 (0.60) | AKR1C3AKR1C2ALDH1A1MAPK1TDP1 | |
| SCHEMBL103644 | 0.81 | CTSD (0.65) | ALDH1A1TDP1MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL10567555 | 0.79 | CTSD (0.62) | ALDH1A1TDP1MEN1KMT2AGAA | |
| Methane SCHEMBL27284103 | 0.79 | CTSD (0.62) | ALDH1A1TDP1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016166-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, CNS DEPRESSANTS | HISAMITSU PHARMACEUTICAL CO., INC. (JA) | 1977-04-05 | — | — | US | disclosed |