Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631419 | 0.84 | WDR5 (0.44) | LMNAALDH1A1NCEH1HPGDSMN1; SMN2 | |
| SCHEMBL11761896 | 0.83 | ALDH1A1 (0.46) | LMNAALDH1A1MAPK1NPY1RNPY2R | |
| SCHEMBL28181518 | 0.81 | HSD17B10 (0.61) | LMNAALDH1A1MAPK1NPY1RNPY2R | |
| SCHEMBL11767248 | 0.81 | ALDH1A1 (0.40) | LMNAALDH1A1MAPK1NPY1RNPY2R | |
| SCHEMBL11764242 | 0.81 | ALDH1A1 (0.41) | LMNAALDH1A1MAPK1NPY1RNPY2R | |
| SCHEMBL11889215 | 0.80 | NCEH1 (0.52) | LMNAALDH1A1NCEH1HPGDSMN1; SMN2 | |
| SCHEMBL21694354 | 0.79 | CA12 (0.53) | LMNAALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL2467190 | 0.79 | NCEH1 (0.54) | LMNAALDH1A1NCEH1HPGDHSD17B10 | |
| SCHEMBL11763250 | 0.79 | HPGD (0.43) | LMNAALDH1A1MAPK1NPY1RNPY2R | |
| SCHEMBL11763832 | 0.79 | TSPO (0.42) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059609-A | HERBICIDE, NEMATOCIDE, FUNGICIDE | PPG INDUSTRIES, INC. (US) | 1977-11-22 | — | — | US | claimed |
| US-4059609-A | HERBICIDE, NEMATOCIDE, FUNGICIDE | PPG INDUSTRIES, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4059609-A | HERBICIDE, NEMATOCIDE, FUNGICIDE | PPG INDUSTRIES, INC. (US) | 1977-11-22 | — | — | US | disclosed |