Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762307 | 0.96 | HDAC3 (0.44) | NPC1LMNARAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL11764839 | 0.90 | HDAC3 (0.41) | HDAC3HDAC1HDAC2EPHX1CNR2 | |
| SCHEMBL11764786 | 0.84 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2EPHX1CNR2 | |
| SCHEMBL11770708 | 0.80 | TP53 (0.49) | NPC1LMNARAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL11038319 | 0.78 | ACHE (0.54) | LMNACETPMAOAMAOBALDH1A1 | |
| SCHEMBL11765167 | 0.77 | ANPEP (0.40) | EPHX1CYP3A4ANPEPALDH1A1KDM4E | |
| SCHEMBL11332669 | 0.77 | ALDH1A1 (0.50) | EPHX1ANPEPALDH1A1KDM4E | |
| SCHEMBL11761705 | 0.77 | HPGD (0.40) | LMNACYP2C9CNR2ALDH1A1 | |
| SCHEMBL3989474 | 0.77 | ALDH1A1 (0.52) | NPC1LMNARAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL11761812 | 0.76 | F2 (0.42) | NPC1LMNARAB9ASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059609-A | HERBICIDE, NEMATOCIDE, FUNGICIDE | PPG INDUSTRIES, INC. (US) | 1977-11-22 | — | — | US | disclosed |