Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998870 | 0.92 | ALDH1A1 (0.54) | ALDH1A1ANPEPTP53RXFP1MAPT | |
| SCHEMBL15682853 | 0.82 | TP53 (0.42) | ALDH1A1TP53RXFP1MAPTLMNA | |
| SCHEMBL11762307 | 0.81 | HDAC3 (0.44) | ALDH1A1ANPEPLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL11764217 | 0.77 | NPC1 (0.44) | ALDH1A1ANPEPLMNASMN1; SMN2CYP3A4 | |
| SCHEMBL9130521 | 0.74 | PDK2 (0.54) | ALDH1A1SMN1; SMN2GAAHPGDNPC1 | |
| SCHEMBL13804898 | 0.73 | MAPT (0.41) | ALDH1A1TP53RXFP1MAPTLMNA | |
| SCHEMBL1269574 | 0.73 | ANPEP (0.65) | ALDH1A1ANPEPRXFP1MAPTLMNA | |
| SCHEMBL1269611 | 0.73 | MEN1 (0.59) | ALDH1A1ANPEPTP53RXFP1MAPT | |
| SCHEMBL11764839 | 0.71 | HDAC3 (0.41) | ALDH1A1ANPEPCNR2 | |
| SCHEMBL11038319 | 0.71 | ACHE (0.54) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009069966-A2 | USE OF COMPOUNDS FOR CONTROLLING THE FUNCTION OF SPHINGOSYLPHOSPHORYLCHOLINE | AMOREPACIFIC CORPORATION (KR) | 2009-06-04 | — | — | WO | claimed |
| WO-2009069966-A2 | USE OF COMPOUNDS FOR CONTROLLING THE FUNCTION OF SPHINGOSYLPHOSPHORYLCHOLINE | AMOREPACIFIC CORPORATION (KR) | 2009-06-04 | — | — | WO | disclosed |