SCHEMBL11764883

SCHEMBL11764883

Cc1ccc(S(=O)(=O)NCP(=O)(O)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.60
CA12 O43570 3/20 0.60
CA9 Q16790 3/20 0.60
CA14 Q9ULX7 1/20 0.60
ALDH1A1 P00352 8/20 0.59
GBA1 P04062 1/20 0.56
MMP1 P03956 2/20 0.55
MMP9 P14780 2/20 0.55
MMP8 P22894 2/20 0.55
MMP13 P45452 2/20 0.55
MMP3 P08254 1/20 0.55
MMP7 P09237 1/20 0.55
MMP14 P50281 1/20 0.55
TSHR P16473 1/20 0.54
CA2 P00918 2/20 0.53
CA1 P00915 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904614 0.82 ALDH1A1 (0.56) MMP2CA9ALDH1A1MMP1MMP9
SCHEMBL6910975 0.82 CA2 (0.60) MMP2CA12CA9CA14ALDH1A1
SCHEMBL6906001 0.81 MMP2 (0.63) MMP2CA12CA9CA14ALDH1A1
SCHEMBL11780882 0.79 ALDH1A1 (0.56) CA12CA9ALDH1A1GBA1TSHR
SCHEMBL6910956 0.79 MMP2 (0.62) MMP2CA12CA9CA14ALDH1A1
SCHEMBL6912549 0.78 CA2 (0.63) MMP2CA12CA9CA14ALDH1A1
SCHEMBL10779723 0.78 ALDH1A1 (0.57) MMP2CA12CA9CA14ALDH1A1
SCHEMBL2627764 0.77 ALDH1A1 (0.68) MMP2CA12CA9ALDH1A1GBA1
SCHEMBL5567042 0.77 ALDH1A1 (0.75) CA12CA9ALDH1A1GBA1CA2
SCHEMBL28686588 0.76 GBA1 (0.67) MMP2CA12CA9ALDH1A1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10464958-B2 Method for the synthesis of alpha-aminoalkylenephosphonic acid MONSANTO TECHNOLOGY LLC (US) 2019-11-05 US claimed
US-20180346497-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC (US) 2018-12-06 US claimed
US-20150232493-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC 2015-08-20 US claimed
US-10464958-B2 Method for the synthesis of alpha-aminoalkylenephosphonic acid MONSANTO TECHNOLOGY LLC (US) 2019-11-05 US disclosed
US-20180346497-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC (US) 2018-12-06 US disclosed
US-20150232493-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID MONSANTO TECHNOLOGY LLC 2015-08-20 US disclosed
EP-2875035-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID Straitmark Holding AG (CH) 2015-05-27 EP disclosed
WO-2014012990-A1 METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID STRAITMARK HOLDING AG (CH) 2014-01-23 WO disclosed
US-4032601-A ACID CATALYSTS MONSANTO COMPANY (US) 1977-06-28 US disclosed