Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821353 | 0.79 | SLC6A2 (0.45) | SMN1; SMN2NPC1TP53RAB9ASLC6A2 | |
| SCHEMBL18009983 | 0.73 | LDHA (0.45) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL3199766 | 0.73 | SLC6A2 (0.50) | NPC1RAB9ASLC6A2SLC6A4SLC2A1 | |
| SCHEMBL7615944 | 0.73 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL8915315 | 0.72 | LDHA (0.47) | CA1CA2SMN1; SMN2NPC1TP53 | |
| SCHEMBL12656352 | 0.72 | CA1 (0.48) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL7282004 | 0.72 | CA1 (0.52) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL11765499 | 0.71 | PAX8 (0.43) | CA1CA2SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL3470955 | 0.71 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL14593916 | 0.70 | SLC2A1 (0.53) | CA1CA2SMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4023956-A | Amide phosphorothiolate herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-05-17 | — | — | US | disclosed |