Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | PARL | Q9H300 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473466 | 0.76 | ALOX12 (0.41) | ALOX12PARLALDH1A1GFERKMT2A | |
| SCHEMBL22974925 | 0.74 | ALOX12 (0.47) | ALOX12PARLALDH1A1GFERKMT2A | |
| SCHEMBL22974934 | 0.74 | ALOX12 (0.47) | ALOX12PARLALDH1A1GFERKMT2A | |
| SCHEMBL20248861 | 0.74 | ALOX12 (0.70) | ALOX12PARLALDH1A1GFERKMT2A | |
| SCHEMBL22974947 | 0.74 | ALOX12 (0.47) | ALOX12PARLALDH1A1GFERKMT2A | |
| SCHEMBL3804000 | 0.74 | GSK3A (0.46) | ALOX12PARLALDH1A1KMT2ATSHR | |
| SCHEMBL436166 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2CA9HPGD | |
| SCHEMBL31703779 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KMT2ASMN1; SMN2CA9HPGD | |
| SCHEMBL19341896 | 0.72 | ALOX12 (0.46) | ALOX12PARLALDH1A1GFERKMT2A | |
| SCHEMBL16684237 | 0.72 | ALOX12 (0.46) | ALOX12PARLALDH1A1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112604004-B | Anti-human EGFR antibody drug conjugate and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-05-10 | — | — | CN | disclosed |
| US-4026798-A | PROLONGING USE | FMC CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |