SCHEMBL19341896

SCHEMBL19341896

O=C1CCC(=O)N1OP(=O)(Oc1ccccc1)ON1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALOX12 P18054 1/20 0.46
▸ PARL Q9H300 3/20 0.43
▸ SRC P12931 1/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.38
▸ ELANE P08246 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.36
▸ GFER P55789 1/20 0.36
▸ KMT2A Q03164 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ CYP3A4 P08684 1/20 0.34
▸ TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123548 0.96 SRC (0.47) ALOX12PARLSRCL3MBTL1TDP1
SCHEMBL19341892 0.76 PARL (0.34) ALOX12PARL
SCHEMBL19341895 0.75 SRC (0.47) SRCL3MBTL1TDP1KDM4EELANE
SCHEMBL29136527 0.74 PARL (0.46) ALOX12PARLL3MBTL1TDP1KDM4E
SCHEMBL6889234 0.73 SRC (0.42) SRCL3MBTL1TDP1KDM4EELANE
Triphenyl Phosphate SCHEMBL483692 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EALDH1A1
Triphenyl Phosphate SCHEMBL28557783 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EALDH1A1
Triphenyl Phosphate SCHEMBL28761613 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EALDH1A1
Triphenyl Phosphate SCHEMBL18116 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL11765374 0.72 ALOX12 (0.55) ALOX12PARLALDH1A1GFERKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544284-B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-01-28 — — US disclosed
US-20170260366-A1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-14 — — US disclosed
US-20170260366-A1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260366-A1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS PFAS, FERMT2, PGM2 ALOX12 351/4885PARL 2070/4885SRC 1639/4885
US-10544284-B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings PFAS, FERMT2, PGM2 ALOX12 351/4885PARL 2070/4885SRC 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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