Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697648 | 0.66 | HSP90AA1 (0.41) | MAPK1HSP90AA1CYP1A2SMN1; SMN2 | |
| SCHEMBL15293970 | 0.64 | MMP2 (0.49) | ALDH1A1PKMPOLBMAPK1HSD17B10 | |
| SCHEMBL8744524 | 0.64 | CASP3 (0.46) | MEN1ALDH1A1KMT2APOLBCASP3 | |
| SCHEMBL454827 | 0.63 | POLB (0.67) | HTTMEN1KMT2APOLBMAPK1 | |
| SCHEMBL11881681 | 0.62 | POLB (0.46) | HTTMEN1KMT2APOLBMAPK1 | |
| SCHEMBL5340450 | 0.62 | POLB (0.46) | HTTMEN1ALDH1A1PKMKMT2A | |
| Potassium Ion SCHEMBL2483202 | 0.62 | POLB (0.46) | HTTMEN1ALDH1A1PKMKMT2A | |
| SCHEMBL2022462 | 0.61 | POLB (0.64) | HTTMEN1KMT2APOLBMAPK1 | |
| SCHEMBL28160078 | 0.61 | POLB (0.64) | HTTMEN1KMT2APOLBMAPK1 | |
| SCHEMBL134793 | 0.61 | POLB (0.56) | HTTMEN1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055409-A | Pyrazole plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-3948937-A | Pyrazole plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |