SCHEMBL11765673

SCHEMBL11765673

N#Cc1c(Cl)c(Cl)c(Cl)c(C#N)c1C#N

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.75
KMT2A Q03164 3/20 0.75
ALDH1A1 P00352 3/20 0.75
MAPT P10636 2/20 0.75
MAPK1 P28482 2/20 0.75
TP53 P04637 1/20 0.75
CYP3A4 P08684 1/20 0.75
HPGD P15428 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
KDM4E B2RXH2 1/20 0.34
HTT P42858 2/20 0.32
GLA P06280 1/20 0.32
TSHR P16473 1/20 0.32
NPY1R P25929 1/20 0.30
NPY2R P49146 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9079137 0.96 MEN1 (0.69) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL29362206 0.96 MEN1 (0.80) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL456703 0.96 MEN1 (0.80) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL6151449 0.89 MEN1 (0.93) MEN1KMT2AALDH1A1MAPTMAPK1
Chlorothalonil SCHEMBL1487631 0.86 MEN1 (1.00) MEN1KMT2AALDH1A1MAPTMAPK1
Chlorothalonil SCHEMBL21254 0.86 MEN1 (1.00) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL18388942 0.86 MEN1 (0.87) MEN1KMT2AALDH1A1MAPTMAPK1
Chlorothalonil SCHEMBL8574863 0.86 MEN1 (1.00) MEN1KMT2AALDH1A1MAPTMAPK1
Chlorothalonil SCHEMBL8200626 0.86 MEN1 (1.00) MEN1KMT2AALDH1A1MAPTMAPK1
SCHEMBL8077195 0.85 MEN1 (0.73) MEN1KMT2AALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3970443-A TETRACHLOROISOPHTHALONITRILE DIAMOND SHAMROCK CORPORATION (US) 1976-07-20 US disclosed