SCHEMBL456703

SCHEMBL456703

N#Cc1c(Cl)c(Cl)c(Cl)c(Cl)c1C#N

nearest known ligand 0.80

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.80
KMT2A Q03164 3/20 0.80
ALDH1A1 P00352 3/20 0.80
MAPK1 P28482 3/20 0.80
MAPT P10636 2/20 0.80
TP53 P04637 1/20 0.80
CYP3A4 P08684 1/20 0.80
HPGD P15428 1/20 0.80
SMN1; SMN2 Q16637 1/20 0.80
KDM4E B2RXH2 1/20 0.36
HTT P42858 2/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
NSD2 O96028 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362206 1.00 MEN1 (0.80) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL11765673 0.96 MEN1 (0.75) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL6151449 0.92 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL9079137 0.92 MEN1 (0.69) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL1487631 0.89 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL18388942 0.89 MEN1 (0.87) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL8574863 0.89 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL8200626 0.89 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL21254 0.89 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL8077195 0.88 MEN1 (0.73) MEN1KMT2AALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120026490-A Porous polyethylene/carbon black composite electrode material and preparation method and application thereof 浙江理工大学 2025-05-23 CN claimed
CN-119390975-A Dispersible covalent triazine skeleton and preparation method and application thereof 人工智能与数字经济广东省实验室(深圳) 2025-02-07 CN claimed
CN-119286047-A Amidoxime functionalized nano-cellulose porous material, and preparation method and application thereof 浙江理工大学 2025-01-10 CN claimed
CN-118812786-A Production process of styrene-acrylic surface glue 贵州同益新型建材有限公司 2024-10-22 CN claimed
CN-118561858-A High water-solubility phthalocyanine modified by amine oxide group, preparation and application thereof 福州大学 2024-08-30 CN claimed
CN-118531524-A Organic micro-nano crystal-based large-area multicolor fluorescence emitting fiber and preparation method and application thereof 苏州大学 2024-08-23 CN claimed
CN-117229517-B Bent structure micro-nano crystal, preparation method and application thereof 苏州大学 2024-06-14 CN claimed
CN-115286638-B Mono-atom Ag antibacterial material based on conjugated phthalocyanine frame and preparation method thereof 王佳玉 2024-03-08 CN claimed
CN-117229517-A Bent structure micro-nano crystal, preparation method and application thereof 苏州大学 2023-12-15 CN claimed
US-20230374043-A1 Hexadeca Ammonium-Modified Phthalocyanine and Preparation Method and Use Thereof as Photodynamic Drug FUZHOU UNIVERSITY (CN) 2023-11-23 US claimed
US-5153350-A Process for preparing 3,4,6-trifluorophithalonitrile PFIZER INC., A CORPORATION OF DE 1992-10-06 US claimed
EP-0198165-B1 WOOD PRESERVATIVE DESOWAG Materialschutz GmbH (DE) 1989-07-05 EP claimed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US claimed
EP-0198165-A1 Wood preservative DESOWAG Materialschutz GmbH (DE) 1986-10-22 EP claimed
US-4572806-A Process for the continuous production of tetrachlorophthalo-nitrile in two reactors in series CAFFARO S.P.A. (IT) 1986-02-25 US claimed
US-4556426-A HALOGENATED AROMATIC DINITRILES TILE COUNCIL OF AMERICA, INC. (US) 1985-12-03 US claimed
US-4485050-A Process for the continuous production of tetrachlorophthalonitrile in a fluidized bed reactor CAFFARO S.P.A. (IT) 1984-11-27 US claimed
US-4239686-A Process for producing phthalimido derivatives ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-12-16 US claimed
US-4201583-A DRY PROCESS, NONSILVER PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4201591-A Electrically activated recording material and process EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374043-A1 Hexadeca Ammonium-Modified Phthalocyanine and Preparation Method and Use Thereof as Photodynamic Drug SLC30A7, SLC7A1, PTMA MEN1 2422/4885KMT2A 139/4885ALDH1A1 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.