SCHEMBL9079137

SCHEMBL9079137

N#Cc1c(Cl)c(Cl)c(C#N)c(C#N)c1C#N

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
ALDH1A1 P00352 3/20 0.69
MAPK1 P28482 3/20 0.69
MAPT P10636 2/20 0.69
TP53 P04637 1/20 0.69
CYP3A4 P08684 1/20 0.69
HPGD P15428 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
KDM4E B2RXH2 1/20 0.36
HTT P42858 2/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
NSD2 O96028 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11765673 0.96 MEN1 (0.75) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL29362206 0.92 MEN1 (0.80) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL456703 0.92 MEN1 (0.80) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL18388942 0.89 MEN1 (0.87) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL1033734 0.88 MEN1 (0.86) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL8077195 0.88 MEN1 (0.73) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL6151449 0.85 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL1487631 0.81 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL21254 0.81 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL8574863 0.81 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523504-A Process for manufacturing alkenyl aromatic compounds COSMO OIL CO., LTD. (JP) 1996-06-04 US claimed
CN-114276531-A Bischloroformate composition and process for producing the same, polycarbonate resin and process for producing the same, electrophotographic photoreceptor and electrophotographic apparatus 出光兴产株式会社 2022-04-05 CN disclosed
US-5523504-A Process for manufacturing alkenyl aromatic compounds COSMO OIL CO., LTD. (JP) 1996-06-04 US disclosed