Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL27874272 | 0.97 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Butyl Alcohol SCHEMBL28064446 | 0.94 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| 1-Hexanol SCHEMBL28320866 | 0.88 | LMNA (0.72) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Dodecanol SCHEMBL27984990 | 0.88 | LMNA (0.72) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Octanol SCHEMBL16516398 | 0.88 | LMNA (0.72) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| 1,4-Butanediol SCHEMBL27858593 | 0.87 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| 1-Hexanol SCHEMBL11007557 | 0.86 | LMNA (0.68) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Hexane SCHEMBL1147860 | 0.84 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| 1,6-Hexanediol SCHEMBL29142100 | 0.84 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 | |
| Propanol SCHEMBL4712985 | 0.83 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658785-A | The separation method of difficult separation system containing triethylamine | 杭州九清科技有限公司 | 2018-10-16 | — | — | CN | claimed |
| US-11718578-B2 | Ketamine flow synthesis | Université de Liège (BE) | 2023-08-08 | — | — | US | disclosed |
| CN-114678487-A | Preparation method of charge transport layer and light emitting diode | TCL科技集团股份有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-20220144751-A1 | Ketamine flow synthesis | GESVAL S.A. (BE) | 2022-05-12 | — | — | US | disclosed |
| US-11286230-B2 | Ketamine flow synthesis | Université de Liège (BE) | 2022-03-29 | — | — | US | disclosed |
| EP-3700887-B1 | PROCESSES FOR THE PREPARATION OF ARYL CYCLOALKYLAMINE DERIVATIVES | UNIV LIEGE (BE) | 2021-08-04 | — | — | EP | disclosed |
| US-20200299224-A1 | Ketamine flow synthesis | GESVAL S.A. (BE) | 2020-09-24 | — | — | US | disclosed |
| EP-3700887-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC MATERIAL | Université de Liège (BE) | 2020-09-02 | — | — | EP | disclosed |
| CN-108658785-B | The separation method of difficult separation system containing triethylamine | 杭州九清科技有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108658785-A | The separation method of difficult separation system containing triethylamine | 杭州九清科技有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-102372851-A | Bridged polysilsesquioxane aerogel and preparation method thereof | CHINESE ACAD INST CHEMISTRY | 2012-03-14 | — | — | CN | disclosed |
| CN-101300258-A | 5-OXO-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA NV (BE) | 2008-11-05 | — | — | CN | disclosed |
| CN-1898243-A | Bicyclic heterocyclic p-38 kinase inhibitors | NOVARTIS AG (CH) | 2007-01-17 | — | — | CN | disclosed |
| CN-1576273-A | Process for Producing Aliprazo | CHONGQING MEDICAL INDUSTRY RES (CN) | 2005-02-09 | — | — | CN | disclosed |
| US-3981828-A | ISOCYANATE TRIMERIZATION CATALYSTS | BASF WYANDOTTE CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11286230-B2 | Ketamine flow synthesis | OPRL1, HTR4, KCNQ4 | ALDH1A1 2512/4885SMN1; SMN2 2908/4885TSHR 1452/4885 |
| US-20200299224-A1 | Ketamine flow synthesis | OPRL1, HTR4, KCNQ4 | ALDH1A1 2512/4885SMN1; SMN2 2908/4885TSHR 1452/4885 |
| US-11718578-B2 | Ketamine flow synthesis | OPRL1, HTR4, KCNQ4 | ALDH1A1 2512/4885SMN1; SMN2 2908/4885TSHR 1452/4885 |
| US-20220144751-A1 | Ketamine flow synthesis | OPRL1, HTR4, KCNQ4 | ALDH1A1 2512/4885SMN1; SMN2 2908/4885TSHR 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.