SCHEMBL11766166

SCHEMBL11766166

C=C(C)c1cc(C(C)C)c(O)c(C(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
GABRA1 P14867 6/20 0.52
GABRB1 P18505 5/20 0.52
GABRB2 P47870 3/20 0.52
GAA P10253 4/20 0.47
LMNA P02545 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
FAAH O00519 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
GABRG2 P18507 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2C P28335 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
HTR2B P41595 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699535 0.83 SMN1; SMN2 (0.43) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL20610938 0.82 CA1 (0.56) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL20610879 0.80 CA1 (0.33) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL2341096 0.77 GABRA1 (0.58) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL20610880 0.77 CA1 (0.56) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL7912415 0.77 HSP90AA1 (0.51) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL14123324 0.75 CA1 (0.30) CA1CA2
SCHEMBL14581596 0.75 CA1 (0.48) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL28078271 0.74 GABRA1 (0.78) CA1CA2GABRA1GABRB1GABRB2
Acetic Acid SCHEMBL1928603 0.74 GABRA1 (0.59) CA1CA2GABRA1GABRB1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039630-A Elastomer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 US claimed
EP-3421450-B1 PHARMACOLOGICALLY ACTIVE COMPOUNDS UNIV LIVERPOOL (GB) 2020-02-05 EP disclosed
US-4039630-A Elastomer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 US disclosed