SCHEMBL7912415

SCHEMBL7912415

C=C(C)c1ccc(O)c(C(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 0.51
HSP90AB1 P08238 4/20 0.51
GABRA1 P14867 4/20 0.43
GABRB2 P47870 3/20 0.43
PTGS1 P23219 2/20 0.40
PTGS2 P35354 1/20 0.40
LMNA P02545 4/20 0.39
SLC6A2 P23975 2/20 0.39
HTR2B P41595 2/20 0.39
TRPA1 O75762 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA1A P35348 1/20 0.39
THRB P10828 4/20 0.38
THRA P10827 3/20 0.38
KDM4E B2RXH2 1/20 0.37
DBH P09172 1/20 0.37
GAA P10253 1/20 0.37
RECQL P46063 1/20 0.37
GABRB1 P18505 2/20 0.37
CA1 P00915 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4776336 0.84 LMNA (0.53) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL7910367 0.83 RORC (0.53) HSP90AA1HSP90AB1PTGS1PTGS2THRB
SCHEMBL7995066 0.82 ELANE (0.37) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL385514 0.80 HSP90AA1 (0.60) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL1408588 0.80 ACE2 (0.38) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL12040101 0.78 HSP90AA1 (0.46) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL28233617 0.78 HSP90AA1 (0.46) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL8655780 0.78 HSP90AA1 (0.62) HSP90AA1HSP90AB1GABRA1GABRB2PTGS1
SCHEMBL11766166 0.77 CA1 (0.56) GABRA1GABRB2PTGS1LMNASLC6A2
SCHEMBL7909292 0.76 CA12 (0.50) PTGS2TRPA1KDM4EDBHGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039630-A Elastomer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 US claimed
US-9405187-B2 Salt, acid generator and resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-02 US disclosed
US-9405187-B2 Salt, acid generator and resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-02 US disclosed
US-8460851-B2 Salt and photoresist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US disclosed
US-8460851-B2 Salt and photoresist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US disclosed
US-20110318688-A1 SALT, ACID GENERATOR AND RESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-29 US disclosed
US-20110318688-A1 SALT, ACID GENERATOR AND RESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-29 US disclosed
US-20110171576-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-14 US disclosed
US-20110171576-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-14 US disclosed
US-20110111342-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-05-12 US disclosed
US-20110111342-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-05-12 US disclosed
US-6211328-B1 IN PRESENCE OF AN ACID GUN EI CHEMICAL INDUSTRY CO., LTD (JP) 2001-04-03 US disclosed
US-4039630-A Elastomer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318688-A1 SALT, ACID GENERATOR AND RESIST COMPOSITION RER1, FGFR1, NHERF1 HSP90AA1 3690/4885HSP90AB1 4188/4885GABRA1 997/4885
US-20110171576-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME CLIC1, SLC10A6, APOL1 HSP90AA1 3863/4885HSP90AB1 4135/4885GABRA1 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.