Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 9/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ap18 5 SCHEMBL1962033 | 0.81 | TRPA1 (1.00) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| Ap18 5 SCHEMBL1499479 | 0.81 | TRPA1 (1.00) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| Ap18 5 SCHEMBL12552586 | 0.81 | TRPA1 (1.00) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| Ap18 5 SCHEMBL29357634 | 0.81 | TRPA1 (1.00) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| Ap18 5 SCHEMBL1499542 | 0.81 | TRPA1 (1.00) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4191604 | 0.76 | TRPA1 (0.53) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10267027 | 0.76 | TRPA1 (0.53) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22995639 | 0.72 | TRPA1 (0.60) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22995643 | 0.72 | TRPA1 (0.60) | TRPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11715595 | 0.71 | TRPA1 (0.58) | TRPA1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012377-A | ANTIMICROBIAL, PARASITICIDES | GLAXO LABORATORIES LIMITED (EN) | 1977-03-15 | — | — | US | disclosed |