Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GCLC | P48506 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378555 | 1.00 | CA2 (0.42) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5363943 | 1.00 | CA2 (0.42) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1176739 | 1.00 | CA2 (0.42) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2183962 | 1.00 | CA2 (0.42) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21218827 | 1.00 | CA2 (0.42) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30629349 | 0.82 | MGLL (0.40) | ALDH1A1 | |
| SCHEMBL30915474 | 0.82 | MGLL (0.40) | ALDH1A1 | |
| SCHEMBL3667634 | 0.81 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7129835 | 0.81 | CA2 (0.55) | CA2MAPK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28483254 | 0.80 | ALDH1A1 (0.34) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | claimed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | claimed |
| EP-0785197-A2 | 2-oxo and 2-thio-1,2-dihydroquinolinyl-oxazolidinones | BAYER AG (DE) | 1997-07-23 | — | — | EP | claimed |
| CN-113121518-B | Preparation method of tedizolid impurity | 北京福元医药股份有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-113045509-B | Industrial production method of linezolid | 上海翰森生物医药科技有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113121518-A | Preparation method of tedizolid impurity | 北京福元医药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113045509-A | Industrial production method of linezolid | 上海翰森生物医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-112543756-A | Substituted oxazolidinones for the treatment of mammalian infections | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |
| US-RE47606-E1 | Process for the preparation of linezolid | OPTIMUS DRUGS PRIVATE LIMITED (IN) | 2019-09-17 | — | — | US | disclosed |
| EP-3250568-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID | Optimus Drugs Pvt Ltd (IN) | 2017-12-06 | — | — | EP | disclosed |
| WO-2017182853-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID | OPTIMUS DRUGS PVT LTD (IN) | 2017-10-26 | — | — | WO | disclosed |
| EP-0694543-A1 | 6-membered N-heteroaryloxazolidinones | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| EP-0694544-A1 | Benzofuranyl- and benzothienyloxazolidinones | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| EP-0693491-A1 | Oxazolidinones substituted by 5-membered heteroaryl group as antibacterial medicine | BAYER AG (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1995007271-A1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | THE UPJOHN COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |
| WO-1993023384-A1 | OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS | THE UPJOHN COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |
| EP-0315831-B1 | METHOD FOR THE PRODUCTION OF A BIOREACTOR AND ITS USE IN THE SEPARATION OF RACEMIC FORMS | BASF Aktiengesellschaft (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0345658-A2 | Processes for preparing a biocatalyst and its use in the separation of racemic mixtures | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |
| EP-0333142-A2 | Process for the preparation of (R)-glycidyl esters | LONZA AG (CH) | 1989-09-20 | — | — | EP | disclosed |
| EP-0315831-A2 | Method for the production of a bioreactor and its use in the separation of racemic forms | BASF Aktiengesellschaft (DE) | 1989-05-17 | — | — | EP | disclosed |