Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11768356

Cc1c(C)c(Cl)c2ccccc2c1C.N

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.38
CYP2A6 P11509 7/20 0.38
MAOA P21397 2/20 0.36
MAOB P27338 1/20 0.36
TSHR P16473 4/20 0.35
ALDH1A1 P00352 4/20 0.35
LMNA P02545 3/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
RAB9A P51151 2/20 0.35
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
ELANE P08246 1/20 0.35
CTSG P08311 1/20 0.35
CTSA P10619 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28671657 0.89 CYP1A2 (0.45) CYP1A2CYP2A6MAOAMAOBTSHR
Ammonia Solution, Strong SCHEMBL2263911 0.84 CYP1A2 (0.50) CYP1A2CYP2A6TSHRALDH1A1LMNA
SCHEMBL31621532 0.82 CYP1A2 (0.39) CYP1A2CYP2A6MAOAMAOBTSHR
SCHEMBL4644475 0.81 MAOA (0.46) CYP1A2CYP2A6MAOAMAOBTSHR
SCHEMBL29660297 0.81 CYP1A2 (0.53) CYP1A2CYP2A6TSHRALDH1A1LMNA
SCHEMBL357443 0.81 CYP1A2 (0.53) CYP1A2CYP2A6TSHRALDH1A1LMNA
SCHEMBL28539881 0.78 CYP1A2 (0.50) CYP1A2CYP2A6TSHRALDH1A1LMNA
SCHEMBL27707210 0.76 ALDH1A1 (0.37) CYP1A2CYP2A6MAOAMAOBTSHR
Hydrazine SCHEMBL394386 0.75 CYP1A2 (0.47) CYP1A2CYP2A6TSHRALDH1A1LMNA
SCHEMBL167933 0.74 CYP1A2 (0.53) CYP1A2CYP2A6TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3996259-A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT THE DOW CHEMICAL COMPANY (US) 1976-12-07 US disclosed