Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768228 | 0.86 | MEN1 (0.38) | MEN1KMT2ATNK2HSD11B1KDM4E | |
| SCHEMBL11774258 | 0.84 | DHFR (0.42) | HSD11B1SLC6A3DHFR | |
| SCHEMBL7231881 | 0.84 | KMT2A (0.40) | MEN1KMT2ATNK2HSD11B1SLC6A3 | |
| SCHEMBL7774785 | 0.84 | KMT2A (0.40) | MEN1KMT2ATNK2HSD11B1SLC6A3 | |
| SCHEMBL11767319 | 0.83 | MEN1 (0.37) | MEN1KMT2ATNK2HSD11B1KDM4E | |
| SCHEMBL14839279 | 0.82 | TNK2 (0.36) | MEN1KMT2ATNK2HSD11B1SLC6A3 | |
| SCHEMBL9875684 | 0.81 | HSD11B1 (0.39) | MEN1KMT2ATNK2HSD11B1SLC6A3 | |
| SCHEMBL11771503 | 0.81 | MEN1 (0.35) | MEN1KMT2ATNK2HSD11B1KDM4E | |
| SCHEMBL11769750 | 0.81 | MEN1 (0.35) | MEN1KMT2ATNK2HSD11B1KDM4E | |
| SCHEMBL11767224 | 0.81 | SLC6A3 (0.40) | MEN1KMT2ATNK2HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940407-A | β-Adrenergic blocking agents in the 1,2,3-thiadiazole series | SYNTEX (U.S.A.) INC. (US) | 1976-02-24 | — | — | US | disclosed |