SCHEMBL11769020

SCHEMBL11769020

CN(CCO)c1nc(Cl)nc(N(C)CCO)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
SLC29A1 Q99808 4/20 0.37
POLB P06746 2/20 0.36
SLC9A5 Q14940 1/20 0.35
MAPT P10636 1/20 0.35
KDM4E B2RXH2 2/20 0.32
HSD17B10 Q99714 3/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
CREBBP Q92793 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031875 0.89 CA12 (0.46) CA12CA1CA2CA9SLC29A1
SCHEMBL11451015 0.88 CA12 (0.41) CA12CA1CA2CA9SLC29A1
SCHEMBL11772001 0.82 LMNA (0.52) CA12CA1CA2CA9SLC29A1
SCHEMBL11764977 0.82 LMNA (0.52) CA12CA1CA2CA9SLC29A1
SCHEMBL11768860 0.80 CA12 (0.42) CA12CA1CA2CA9SLC29A1
SCHEMBL11765891 0.80 CA12 (0.42) CA12CA1CA2CA9SLC29A1
SCHEMBL2844607 0.78 CA12 (0.44) CA12CA1CA2CA9SLC29A1
SCHEMBL6966357 0.77 SLC29A1 (0.48) SLC29A1MAPTKDM4EHSD17B10CYP2C9
SCHEMBL15248597 0.77 CA12 (0.33) CA12CA1CA2CA9ALDH1A1
SCHEMBL11766055 0.77 SLC29A1 (0.52) CA12CA1CA2CA9SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3981829-A CATALYST SYSTEM OF ALKANOLAMINOTRIAZINE, HEXAHYDROTRIAZINE, A PHENOL BASF WYANDOTTE CORPORATION (US) 1976-09-21 US disclosed