SCHEMBL11768860

SCHEMBL11768860

CN(CCO)c1nc(O)nc(N(C)CCO)n1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
SLC29A1 Q99808 5/20 0.38
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 3/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
CREBBP Q92793 1/20 0.32
ALDH1A1 P00352 1/20 0.32
EHMT2 Q96KQ7 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31
NAPEPLD Q6IQ20 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031875 0.91 CA12 (0.46) CA12CA1CA2CA9SLC29A1
SCHEMBL11772001 0.84 LMNA (0.52) CA12CA1CA2CA9SLC29A1
SCHEMBL11764977 0.84 LMNA (0.52) CA12CA1CA2CA9SLC29A1
SCHEMBL11765891 0.82 CA12 (0.42) CA12CA1CA2CA9SLC29A1
SCHEMBL2844607 0.80 CA12 (0.44) CA12CA1CA2CA9SLC29A1
SCHEMBL11769020 0.80 CA12 (0.49) CA12CA1CA2CA9SLC29A1
SCHEMBL11766112 0.78 SLC29A1 (0.52) CA12CA1CA2CA9SLC29A1
SCHEMBL11766055 0.78 SLC29A1 (0.52) CA12CA1CA2CA9SLC29A1
SCHEMBL11765516 0.77 ALDH1A1 (0.39) CA12CA1CA2CA9SLC29A1
SCHEMBL11668373 0.77 CA12 (0.39) CA12CA1CA2CA9SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3981829-A CATALYST SYSTEM OF ALKANOLAMINOTRIAZINE, HEXAHYDROTRIAZINE, A PHENOL BASF WYANDOTTE CORPORATION (US) 1976-09-21 US disclosed