Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764977 | 1.00 | LMNA (0.52) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL1031875 | 0.93 | CA12 (0.46) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL4151814 | 0.85 | LMNA (0.65) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL11765891 | 0.84 | CA12 (0.42) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL11768860 | 0.84 | CA12 (0.42) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL2844607 | 0.82 | CA12 (0.44) | SLC29A1CA12CA1CA2CA9 | |
| SCHEMBL11769020 | 0.82 | CA12 (0.49) | LMNACYP1A2THRBBLMCREBBP | |
| SCHEMBL11766112 | 0.80 | SLC29A1 (0.52) | SLC29A1CA12CA1CA2CA9 | |
| SCHEMBL11766055 | 0.80 | SLC29A1 (0.52) | SLC29A1CA12CA1CA2CA9 | |
| SCHEMBL1309901 | 0.80 | LMNA (0.58) | LMNACYP1A2THRBBLMCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981829-A | CATALYST SYSTEM OF ALKANOLAMINOTRIAZINE, HEXAHYDROTRIAZINE, A PHENOL | BASF WYANDOTTE CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |