Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11767777 | 0.84 | KMT2A (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11767760 | 0.84 | KMT2A (0.44) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11768663 | 0.82 | KMT2A (0.43) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11767147 | 0.82 | KAT2B (0.46) | TERTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11766710 | 0.82 | TERT (0.43) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL11770423 | 0.81 | RAD52 (0.63) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL29628876 | 0.81 | RAD52 (0.63) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| SCHEMBL11799355 | 0.80 | TERT (0.51) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11767352 | 0.80 | ALDH1A1 (0.43) | CHRM2CHRM1DRD2ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL10942278 | 0.80 | RAD52 (0.62) | CHRM2CHRM1DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013665-A | ANTIVIRAL, SUBSTITUTED 1,3-DIMETHYL-1H-PYRAZOLO(3,4B)QUINOLINES | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |