Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766710 | 0.87 | TERT (0.43) | TERTNPC1KMT2AHTR2CPOLB | |
| Hydrochloric Acid SCHEMBL11767777 | 0.83 | KMT2A (0.44) | TERTNPC1KMT2AMEN1HTR2C | |
| Hydrochloric Acid SCHEMBL11767760 | 0.83 | KMT2A (0.44) | TERTNPC1KMT2AMEN1HTR2C | |
| Hydrochloric Acid SCHEMBL11768663 | 0.82 | KMT2A (0.43) | TERTPDE5ANPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11767147 | 0.81 | KAT2B (0.46) | TERTNPC1KMT2AMEN1POLB | |
| SCHEMBL11769166 | 0.80 | CHRM2 (0.48) | TERTPDE5ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL11770423 | 0.80 | RAD52 (0.63) | TERTNPC1KMT2AHTR2CPOLB | |
| SCHEMBL29628876 | 0.80 | RAD52 (0.63) | TERTNPC1KMT2AHTR2CPOLB | |
| Hydrochloric Acid SCHEMBL11767352 | 0.79 | ALDH1A1 (0.43) | TERTNPC1KMT2AMEN1HTR2C | |
| Hydrochloric Acid SCHEMBL10942278 | 0.79 | RAD52 (0.62) | TERTNPC1KMT2AHTR2CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013665-A | ANTIVIRAL, SUBSTITUTED 1,3-DIMETHYL-1H-PYRAZOLO(3,4B)QUINOLINES | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |