Oxirane

Oxirane

SCHEMBL11769488

C1CO1.c1ccc2cc(COCc3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 10/20 0.49
SLC6A2 P23975 3/20 0.49
SLC6A4 P31645 3/20 0.49
SLC6A3 Q01959 3/20 0.49
HTR2A P28223 1/20 0.49
HTR2C P28335 1/20 0.49
HTR7 P34969 1/20 0.49
HTR2B P41595 1/20 0.49
HTR3A P46098 1/20 0.49
HTR4 Q13639 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
KCNH2 Q12809 2/20 0.46
RAB9A P51151 1/20 0.46
TACR1 P25103 2/20 0.43
KMT2A Q03164 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL433146 0.90 CYP1A2 (0.58) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7648436 0.84 TSHR (0.62) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL16174483 0.80 CYP1A2 (0.52) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL13977956 0.78 CYP1A2 (0.50) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL19249290 0.78 CYP1A2 (0.50) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL19508917 0.78 CYP1A2 (0.50) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL19249099 0.78 CYP1A2 (0.50) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL2108042 0.78 CYP1A2 (0.50) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL19249093 0.78 CYP1A2 (0.50) ALOX5SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL28367677 0.78 RAB9A (0.51) ALOX5SLC6A2SLC6A4SLC6A3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4011082-A SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JA) 1977-03-08 US claimed