Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433146 | 0.87 | CYP1A2 (0.58) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL28367677 | 0.84 | RAB9A (0.51) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL7648436 | 0.82 | TSHR (0.62) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL16174483 | 0.82 | CYP1A2 (0.52) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19249093 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19249099 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL2108042 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL19249290 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL13977956 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 | |
| SCHEMBL4177442 | 0.80 | CYP1A2 (0.61) | CYP1A2CYP2A6RAB9ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305809-A1 | AGENT FOR INTRODUCING PROTECTING GROUP FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305809-A1 | AGENT FOR INTRODUCING PROTECTING GROUP FOR HYDROXY GROUP AND/OR MERCAPTO GROUP | GRHPR, AOX1, MSRB3 | CYP1A2 262/4885CYP2A6 214/4885RAB9A 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.