Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381658 | 0.83 | DHFR (0.45) | DHFRMEN1KMT2ATNK2ALDH1A1 | |
| SCHEMBL16482755 | 0.82 | ICAM1 (0.40) | MEN1KMT2AKIF11ALDH1A1KDM4C | |
| SCHEMBL3500438 | 0.82 | TNK2 (0.44) | DHFRMEN1KMT2ATNK2ALDH1A1 | |
| SCHEMBL5702480 | 0.80 | DDB1 (0.41) | DHFRMEN1KMT2ATNK2KDM4C | |
| SCHEMBL883393 | 0.80 | DHFR (0.41) | DHFRMEN1KMT2ATNK2ALDH1A1 | |
| SCHEMBL862862 | 0.80 | MEN1 (0.43) | DHFRMEN1KMT2ATNK2ALDH1A1 | |
| SCHEMBL3143065 | 0.80 | HRH3 (0.52) | MEN1KMT2ATNK2SMN1; SMN2HRH3 | |
| SCHEMBL3139148 | 0.80 | DHFR (0.46) | DHFRMEN1KMT2ATNK2ALDH1A1 | |
| SCHEMBL7774639 | 0.80 | DDB1 (0.41) | DHFRMEN1KMT2ATNK2KDM4C | |
| SCHEMBL9141643 | 0.80 | KDM4C (0.46) | MEN1KMT2AKIF11ALDH1A1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940407-A | β-Adrenergic blocking agents in the 1,2,3-thiadiazole series | SYNTEX (U.S.A.) INC. (US) | 1976-02-24 | — | — | US | disclosed |