Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520855 | 0.73 | TSHR (0.38) | ALDH1A1MAPTRAB9ARIPK1GAA | |
| SCHEMBL10099709 | 0.68 | MAPT (0.43) | ALDH1A1MAPTRAB9ARIPK1L3MBTL1 | |
| SCHEMBL18153203 | 0.67 | HTR2A (0.44) | ALDH1A1MAPTNPC1RAB9AHTR2A | |
| SCHEMBL29987788 | 0.63 | HTR2A (0.59) | ALDH1A1MAPTNPC1RAB9AHTR2A | |
| SCHEMBL18153233 | 0.63 | HTR2A (0.59) | ALDH1A1MAPTNPC1RAB9AHTR2A | |
| SCHEMBL11377237 | 0.60 | HTR2A (0.57) | ALDH1A1RAB9AHTR2AHTR2CHTR2B | |
| SCHEMBL30998375 | 0.59 | CRBN (0.57) | ALDH1A1MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL1265365 | 0.59 | CRBN (0.57) | ALDH1A1MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL1265364 | 0.59 | CRBN (0.57) | ALDH1A1MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL19312323 | 0.58 | BRD4 (0.45) | ALDH1A1HTR2AHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055409-A | Pyrazole plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-3948937-A | Pyrazole plant growth regulants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |