Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558949 | 0.88 | ALDH1A1 (0.48) | ALDH1A1ALOX15TSHRHPGDKDM4E | |
| SCHEMBL1567403 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRHPGDKDM4E | |
| SCHEMBL11443844 | 0.77 | GABRA1 (0.40) | ALDH1A1TSHRHPGDCYP3A4LMNA | |
| SCHEMBL16466774 | 0.77 | LMNA (0.45) | ALDH1A1ALOX15TSHRHPGDKDM4E | |
| SCHEMBL9017947 | 0.76 | ACE2 (0.38) | ALDH1A1ALOX15TSHRKDM4EMAPT | |
| SCHEMBL11140775 | 0.76 | TSHR (0.37) | ALDH1A1ALOX15TSHRHPGDKDM4E | |
| SCHEMBL27900404 | 0.76 | TSHR (0.49) | ALDH1A1ALOX15TSHRHPGDMAPT | |
| SCHEMBL3389839 | 0.76 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRHPGDKDM4E | |
| SCHEMBL28119639 | 0.76 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL9117656 | 0.76 | LMNA (0.43) | ALDH1A1ALOX15TSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959351-A | INSECTICIDE, CHOLINESTERASE INHIBITOR | RESEARCH CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |