Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779422 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11775838 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10577616 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11776024 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11775977 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10840481 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL26078910 | 0.71 | CHEK1 (0.53) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5819155 | 0.70 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10842636 | 0.69 | POLB (0.51) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10149199 | 0.68 | SMN1; SMN2 (0.53) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953457-A | S-TRIAZOLO(4,3-A)QUINOLINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |