Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843630 | 0.84 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10842419 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10842636 | 0.80 | POLB (0.51) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10843797 | 0.78 | ALDH1A1 (0.40) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10842100 | 0.78 | NPC1 (0.37) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11779422 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11773777 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10577616 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11775838 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11776024 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174833-A2 | Triazoloquinoline derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |