Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.57 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779422 | 0.73 | KDM4E (0.61) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11775977 | 0.71 | KDM4E (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11776024 | 0.70 | KDM4E (0.58) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11773777 | 0.70 | KDM4E (0.58) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10577616 | 0.70 | KDM4E (0.58) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11775838 | 0.70 | KDM4E (0.58) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5814566 | 0.68 | RECQL (0.62) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL10574725 | 0.67 | MAPT (0.49) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5818702 | 0.66 | RAB9A (0.58) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10840481 | 0.65 | KDM4E (0.52) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |